{"id":3067,"date":"2020-10-20T13:11:43","date_gmt":"2020-10-20T13:11:43","guid":{"rendered":"https:\/\/www.trincoll.edu\/alumniandfamilies\/?page_id=3067"},"modified":"2020-10-20T13:28:25","modified_gmt":"2020-10-20T13:28:25","slug":"josiahhornblower00","status":"publish","type":"page","link":"https:\/\/www.trincoll.edu\/alumniandfamilies\/virtuallongwalk\/bantamcheckins\/josiahhornblower00\/","title":{"rendered":"Bantam Check-In with Josiah Hornblower &#8217;00"},"content":{"rendered":"<p>When Josiah Hornblower &#8217;00 arrived at Trinity, he never imagined he would one day co-found a successful biotechnology company. His grandmother was a blood research scientist, and as a child he tagged along to her research lab, marveling at her rapt concentration amid the mysterious vials and test tubes. But his interest in science waned, despite taking science classes in high school. At Trinity he took just one science class during the last semester of his senior year. His major was art history.<\/p>\n<p>What drew him initially to art history classes was the atmosphere. He still remembers those dim rooms and the mesmerizing glow of projector slides. \u201cIt was soothing,&#8221; he says, &#8220;sitting in the dark like that.\u201d His first art history class brought students on a journey from antiquity to modernity, sparking a fascination that carried him through graduation. \u201cArt history was an incredible way to study history and humanity,&#8221; says Hornblower. &#8220;Works of art can be the most primary sources.&#8221;<\/p>\n<p>That interest in getting to the root of the information, the primary source, would later serve Hornblower well. His career trajectory is the product of his own intellectual curiosity, which he first fostered at Trinity. Upon graduation, like many of his classmates, Hornblower moved to New York City and began a career in finance. He found that he did well with investments in industries he was fascinated by. In the early 2000s, for instance, he delved into groundbreaking work relating to the human immune system. He read all he could, investigating the companies involved and their latest innovations. Hornblower thinks of this period as a critical supplement to his liberal arts education. \u201cI call that my graduate degree from the university of life,\u201d he says.<\/p>\n<p>With this newfound information, he started investing in oncology and genetics research and the associated technologies. \u201cPeople think I don\u2019t know anything about science because I didn\u2019t study it. But I probably put more hours in studying than the average Ph.D.!\u201d While learning more about the medical and science fields, he reconnected with Taylor Schreiber, a classmate from St. Paul\u2019s School, and started a small company called Pelican Therapeutics.<\/p>\n<p>The idea for the company had come during a hike with the two friends. They decided to pursue a grant and wound up being awarded a $15.2 million contract from the State of Texas for clinical trials based on their research in cancer immunotherapy. Hornblower ran Pelican&#8217;s business and financial side while Schreiber pursued groundbreaking research on T-cells and the inflammatory responses of the immune system.<\/p>\n<p>Ultimately, Hornblower and Schreiber\u2019s work with Pelican wound up seeding a larger project\u2014Shattuck Labs, which they founded in 2016. Shattuck has allowed them to expand their work, and build molecules that are multifunctional, allowing multiple therapeutic mechanisms to synergize to provide potentially more effective treatments for cancer patients.<\/p>\n<p>Hornblower compares Shattuck\u2019s biotech innovations to the strategy employed by Apple. \u201cWhile technically genius, Apple\u2019s breakthrough was conceptually very simple,\u201d he says, \u201c they asked whether it was possible to consolidate a cell phone, a digital camera, and a MP3 player into a single device. Shattuck\u2019s innovation is similar, and we\u2019ve figured out how to stich complementary elements that separately enhance immune responses against cancer and make them work together more effectively in a single drug.\u201d Shattuck has built over 300 unique molecules using its platform technology, and is now actively investigating its molecules in three clinical trials in cancer patients. The company Hornblower and Schreiber built has now become an emerging major player in its field, partnering with larger companies to innovate on a broader scale.<\/p>\n<figure id=\"attachment_3068\" aria-describedby=\"caption-attachment-3068\" style=\"width: 640px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-3068 size-large\" src=\"https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-767x1024.jpg\" alt=\"Hornblower and Schreiber in front of a mountainous landscape.\" width=\"640\" height=\"854\" srcset=\"https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-767x1024.jpg 767w, https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-225x300.jpg 225w, https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-768x1025.jpg 768w, https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-735x980.jpg 735w, https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001-555x740.jpg 555w, https:\/\/www.trincoll.edu\/alumniandfamilies\/wp-content\/uploads\/sites\/30\/2020\/10\/thumbnail_image001.jpg 959w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption id=\"caption-attachment-3068\" class=\"wp-caption-text\">Hornblower (right) and Schreiber (left) on a hike&#8211; it was on one of these treks that the idea for Pelican Therapeutics was born.<\/figcaption><\/figure>\n<p>Despite the recent worldwide turmoil, Hornblower remains optimistic about Shattuck&#8217;s future. \u00a0\u201cThe world has changed and the investment world has changed. But to folks in oncology, and its related capital market activity, healthcare technology has become even more important.\u201d Just recently in October, Shattuck went public through an IPO on the NASADQ raising over $200 million from premier public investors.<\/p>\n<p>From art history to entrepreneurship, this alum can look back to Trinity and trace the roots of his success. \u201cTrinity\u2019s greatest qualities, for me, were its high-caliber teachers and academic opportunities,\u201d says Hornblower. \u201cMy experience at Trinity was that liberal arts teaches you about people and humanity, philosophers and artists. The world is your oyster.\u201d<\/p>\n<p>Hornblower believes his fellow students were also essential to his education. After entering Trinity as a shy teenager, Hornblower grew comfortable interacting and exchanging ideas with a broad range of personalities with various interests and backgrounds. \u201cIt\u2019s a school where you\u2019re around people with a high social EQ and IQ,&#8221; he says. &#8220;This accelerated my ability to learn, get involved, and try new things.\u201d He feels this social experience served him well in growing his companies, wooing investors, and recruiting an impressive board of directors and leadership team at Shattuck.<\/p>\n<p>Hornblower recently stepped back from actively running Shattuck and now serves as Executive Chairman. Yet he remains passionate about the company and its further impact in the years ahead. Meanwhile, Hornblower is looking forward to the next project on his horizon. Wherever that venture may lie, his deep love of learning \u2013 inculcated amid masterpieces of art and the soothing glow of slide projectors \u2013 will take him there.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When Josiah Hornblower &#8217;00 arrived at Trinity, he never imagined he would one day co-found a successful biotechnology company. His grandmother was a blood research scientist, and as a child he tagged along to her research lab, marveling at her rapt concentration amid the mysterious vials and test tubes. But his interest in science waned, [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":0,"parent":2154,"menu_order":16,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3067","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.5 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Bantam Check-In with Josiah Hornblower &#039;00 - Alumni and Families<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.trincoll.edu\/alumniandfamilies\/virtuallongwalk\/bantamcheckins\/josiahhornblower00\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bantam Check-In with Josiah Hornblower &#039;00\" \/>\n<meta property=\"og:description\" content=\"When Josiah Hornblower &#8217;00 arrived at Trinity, he never imagined he would one day co-found a successful biotechnology company. 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