B.S. Biomedical Engineering, Boston University, 1982
M.S.E. Bioengineering, University of Pennsylvania, 1984
Ph.D. Engineering, University of Pennsylvania, 1990
Teaching Interests:
Mechanics, biomechanics, fluid mechanics and instrumentation
Research Interests:
Biomechanics, cardiovascular dynamics, muscle contraction and physiological modeling
Professor Palladino conducts research in the field of cardiovascular system
dynamics including mechanical description of the heart as a pump, heart-vessel
interaction and control of the cardiovascular system, muscle contraction
mechanisms, biomechanics, and noninvasive measurements. He collaborates
with the Cardiovascular Studies Unit at the University of Pennsylvania and
Rutgers University and with clinical and mathematical researchers in Leuven,
Belgium and Copenhagen, Denmark. Dr. Palladino is a member of the American
Society of Mechanical Engineers, the Biomedical Engineering Society, the
Cardiovascular System Dynamics Society, the Engineering in Medicine and
Biology Society (EMBS), the European Society for Noninvasive Cardiovascular
Dynamics, The Connecticut Academy of Science and Engineering and Sigma Xi.
He serves as a peer reviewer for the National Science Foundation, the American
Journal of Physiology, the Annals of Biomedical Engineering, and the IEEE
Transactions on Biomedical Engineering. His research has been funded
by the NIH, NSF, NASA, the Connecticut Department Of Higher Education and
the Howard Hughes Medical Institute.
Selected Recent Publications:
Palladino, J.L., Mulier, J.P., Wu, F., Moser, M., Kenner,
T., Baevsky, R.M. and Noordergraaf, A.: Assessing the state of the circulatory
system via parameters vs. variables (invited paper). J. Cardiovasc.
Diag. Proc. 13(2)131-139, 1996.
Palladino, J.L., Mulier, J.P. and Noordergraaf, A.: Closed-loop systemic circulation model using the Frank. Mathematical Models in Physiology, special issue Surv. Math. Indust., 7:177-186, Springer Verlag 1997.
Palladino, J.L. and Noordergraaf, A. Muscle contraction mechanics from ultrastructural dynamics. Chapter 3 in: Analysis and Assessment of Cardiovascular Function, G. Drzewiecki and J. K-J Li, eds., Springer-Verlag, pp. 33-57, 1998.
Palladino, J.L., Mulier, J.P., and Noordergraaf, A.: Defining ventricular elastance. Proc. 20th Int. Conf. IEEE Engineering and Medicine in Biology Society, Hong Kong, pp. 383-386, 1998.
Palladino, J.L. and Noordergraaf, A.: The changing view of the heart through the centuries. in: Mathematical Modelling in Medicine, M. Danielsen and J.T. Ottesen, eds., IOS Press, Amsterdam, pp. 3-11, 2000.
Danielsen, M., Palladino, J.L., and Noordergraaf, A.: The left ventricular ejection effect. in: Mathematical Modelling in Medicine, M. Danielsen and J.T. Ottesen, eds., IOS Press, Amsterdam, pp. 13-28, 2000.
Palladino, J.L., Ribeiro, L.C. and Noordergraaf, A.: Human circulatory system model based on Frank's mechanism. in: Mathematical Modelling in Medicine, M. Danielsen and J.T. Ottesen, eds., IOS Press, Amsterdam, pp. 29-40, 2000.
Palladino, J.L. and Davis, R.B.D: Biomechanics, Chapter 9 in: Introduction to Biomedical Engineering, J.D. Enderle, S.M. Blanchard and J.D. Bronzino, eds., Academic Press, NY, pp. 411-465, 2000.
Palladino, J.L.: Physiological Modeling, Simulation and Control, in: The Biomedical Handbook (2ed.), J.D. Bronzino, ed., CRC Press, Boca Raton, FL, pp. XVI1-3, 2000.
Palladino, J.L., Drzewiecki, G.M. and Noordergraaf, A.: Modeling Strategies in Physiology, Chapter 156 in: The Biomedical Handbook (2ed.), J.D. Bronzino, ed., CRC Press, Boca Raton, FL, pp. 158/1-18, 2000.
Palladino, J.L. and Noordergraaf, A.: A paradigm for quantifying ventricular contraction. Proc. Int. Conf. On Life Sci., Slovenian Biophysical Soc., Gozd Martuljek, Slovenia, p. 94, 2001.
Palladino, J.L. and Noordergraaf, A.: Ventricular pumping and heart muscle dynamics. Proc. SIAM Life Sciences Conf., Boston, MA, MS17, p. 94, 2002.
Palladino, J.L. and Noordergraaf, A.: A paradigm for quantifying ventricular contraction. Cell. Mole. Biol. Letters 7(2):331-335, 2002.
Palladino, J.L. and Noordergraaf, A.: Cardiovascular system modeling: concise analytical description of the closed circulation. Int. J. Cardiovasc. Med. Sci. 6(2):52, 2003.
Bovard, M.S., Connell, W.R., Moore, S.E. and Palladino, J.L.: Quantifying impedance defined flow. Proc. 30th IEEE Northeast Bioeng. Conf., Springfield, MA, pp.192-193, 2004.
Recent Funding:
NASA Experimental Program to Stimulate Competitive Research (EPSCoR) Preparation Grant,1999, Project Title: Dynamic Modeling of Structures.
Danish Heart Foundation, 1999-2000 Project Title: The Ventricular Ejection Effect. Support for post-doc Michael Danielsen, for joint cardiovascular research at Trinity.
NASA Experimental Program to Stimulate Competitive Research (EPSCoR) Preparation Grant, 2000, Project Title: Dynamic Modeling of Structures.
Danish Heart Foundation, 2000-2001 (post-doc renewal) Project Title: The Ventricular Ejection Effect. Support for post-doc Dr. Michael Danielsen, Visiting Asst. Professor of Engineering.
NASA Experimental Program to Stimulate Competitive Research (EPSCoR) Core Funding Grant,2002, Project Title: Cardiovascular Dynamics in Space Flight and Microgravity.
Howard Hughes Medical Institute Grant, co-PI, 2004-2008, Project Title: Physiological Modeling
