RICHARD V. PRIGODICH - CURRICULUM VITAE

 

EDUCATION          B.S. Chemistry, Lake Forest College, Lake Forest, IL, 1974

                              Ph.D. Chemistry, Wesleyan University, Middletown, CT, 1982 

                              NIH Post-Doctoral Fellowship, Yale University, 1982-85

 

AWARDS AND       Adjunct Research Professor, University of Massachusetts, 1994

FELLOWSHIPS       NIH Senior International Fellow, Oxford University, 1990

                              Visiting Scientist Award, Yale University, 1986

                              NIH Post-Doctoral Fellowship, Yale University, 1982-85

                              Petersson Fellowship, Wesleyan University, 1981

                              Phi Beta Kappa, Lake Forest College, 1974

 

PROFESSIONAL    2001-          Professor of Chemistry, Trinity College

EXPERIENCE        1994-05      Chair, Chemistry Department, Trinity College      

                              1992-01      Associate Professor of Chemistry, Trinity College

                              1985-91      Assistant Professor of Chemistry, Trinity College

                              1982-85      NIH Post-Doctoral Fellow, Yale University

                              1978-82      Ph.D. Chemistry, Wesleyan University

                              1976-77      Analytical Chemist, Colt Industries,

                              1975-76      Teacher, Marvelwood School

                              1974-75      Teacher, Perkins School for the Blind

 

TEACHING  The teaching load at Trinity College is five three-semester hour courses per year.  Professor Prigodich's teaching load is a variable combination of five of the following courses: Introductory Chemistry I and II, Introductory Chemistry I and II Laboratory, Physical Chemistry I and II, Physical Chemistry Laboratory, Physical Biochemistry, Physical Biochemistry Laboratory, Molecular Spectroscopy, Molecular Spectroscopy Laboratory, Magnetic Resonance, Magnetic Resonance Laboratory, Biological Chemistry, and First Year Seminars.

 

SCHOLARSHIP  The physical biochemistry of protein-ligand interactions.  The two major research projects currently being investigated focus on: the elucidation of the binding sites of a class of proteins involved in the replication, recombination and repair of DNA that bind single-stranded DNA, and the structure and binding sites of a small protein of unknown function found in high concentration in bone known as osteocalcin.  Various physical techniques are used in these studies including: high resolution solution nuclear magnetic resonance (NMR), solid state NMR, circular dichroism, fluorimetry, x-ray powder diffraction, capillary zone electrophoresis, DNA synthesis, peptide synthesis, atomic force microscopy, ICP, mass spectrometry and infra-red spectroscopy.

 

 

 

SUMMARY OF TEACHING AND SERVICE ACCOMPLISHMENTS

 

New Courses Taught

Established two new laboratory courses:     CHEM 309L- Physical Chemistry I

                                                              CHEM 316L- Physical Biochemistry

Established new upper level courses:          CHEM 418  - Magnetic Resonance    

                                                              CHEM 404  - Biochemical Evolution

                                                              CHEM 404  - Protein Structure & Function

First Year Seminars:                                AIDS: An Overview               

                                                              Origin of Life

Sophomore year ISP seminar                    Living with AIDS in the 21st Century

                         

Contributions to Departmental Curriculum and Teaching

Twelve years' as department chair.  As chair helped initiate and direct department-wide discussions regarding the department's rededication to and revamping of the first year CHEM 111 - CHEM 112 sequence.  Was involved in the original design of this lab-directed lecture course and has taught both sections several times.  Inaugurated student research seminar program and departmental student advising sessions.  Oversaw raising funds and endowments for purchase of major additions to departmental capital equipment inventory.  Oversaw renovation plan for teaching laboratories.  Supported the establishment of the Supplemental Instruction Program.  Helped establish a vibrant and productive departmental summer research program for undergraduates.

 

Contributions to College's Science Curriculum

Served on the Science Alliance Steering Committee for six years and acted as interim director for one year.  Participated in original discussions and planning that led to the establishment of ISP.  Directed discussions among science faculty that led to the science departmentsÕ concerted effort to establish an Environmental Science Program.

 

Contributions to College Curriculum

Served on Curriculum Committee for eleven years and one year as chair.  Served on

many Curriculum Committee subcommittees.

Served on the Educational Policy Committee for two years and one year as chair.

Served on the college wide Curriculum Review Committee (2002).

 

Other Service to the College

Co-chair of the faculty/trustee Special Committee on Institutional Administration and    Governance (2004).

Served on Faculty Research Committee for four years.

Was a founding member of the Math Center Advisory Committee.

Was a founding member of the MVP, Mentors for Violence Prevention Program.

Was a founding member of the TCCTR and Human Rights Program steering committees.

Has served on other ad hoc committees at the request of Presidents and Deans.

 

INVITED LECTURES

 

"Osteocalcin and the Molecular Structure of Bone Tissue"

University of Newcastle – 2000

 

"Studies on the Molecular Structure of Bone Tissue"

SUNY Stony Brook – 1999

 

"Interactions of Osteocalcin with Bone Tissue Macromolecules"

University of Connecticut – 1997

 

"Footprinting Single-Stranded DNA Binding Proteins"

Lake Forest College – 1995

 

"Towards a Solution Structure of Osteocalcin"

Rhode Island College - 1991

 

"Solid State NMR Studies of Cadmium Analogs of Hydroxyapatite"

Oxford University - 1990

 

"Reactions of Single-Stranded DNA with Hydroxyl Radical"

Northeast Regional Meeting of the American Chemical Society

University of Massachusetts, Amherst - 1989

 

"1H, 31P and 113Cd Solution NMR Studies of Osteocalcin"

Wesleyan University – 1986

 

ABSTRACTS OF POSTER PRESENTATIONS AT CONFERENCES

 

ÒDegradation of intra-crystalline proteins: molecular clocks?Ó

Mike Buckley, Enrico Cappellini, Jane Thomas-Oates, Peggy Ostrom, Kirsty Penkman, Richard Prigodich, Matthew Collins*

Gordon Research Conference – Biomineralization – 2006

 

"Synthesis of 5-5'-di-tert-butyl-N-(9-fluorenylmethyloxycarbonyl)-4-carboxyglutamateÓ

Frank Mieles* and Nicholas Callahan* and Richard V. Prigodich

ACS National Meeting – 2006

 

"FT-IR analysis of Osteocalcin Secondary StructureÓ

William Roux* and Richard V. Prigodich

ACS National Meeting – 2005

 

 

 

"Binding Studies of N-terminal Osteocalcin Peptides to type I CollagenÓ

Anthony Belanger* and Richard V. Prigodich

ACS National Meeting – 2003

 

"Footprinting EcoSSB bound to Fluorescently-labeled ssDNA via

LIF Capillary Electrophoresis"

R. V. Prigodich and E. Derbyshire*

3rd European Biophysics Congress - 2000

 

"Evidence for the Preferential Depletion of the Metal(II) Site

in Non-Stoichiometric Apatites"

Richard V. Prigodich and Peter Chupas*

XXVIth European Symposium on Calcified Tissue – 1999

 

"Footprinting Single-Stranded DNA / SSB Complexes via Capillary Electrophoresis"

Richard V. Prigodich and Sayura Aoyagi*

Northeast Regional Meeting of the American Chemical Society - 1997

 

"Characterizing the Complex of Bovine Osteocalcin and Type I Collagen"

Richard V. Prigodich and Mark Vesely*

Arthritis Foundation Biennial Conference - 1995

 

"Solution Strucuture of Osteocalcin"

Richard V. Prigodich and Douglas Macdonald*

Arthritis Foundation Biennial Conference - 1993

 

"Footprinting the Complex of E. coli SSB and ssDNA"

Richard V. Prigodich and Craig T. Martin

11th International Biophysics Congress – 1993

 

"The Binding of Bovine Osteocalcin to Type I Collagen"

Richard V. Prigodich and Mark Vesely*

Gordon Research Conference on Bones and Teeth - 1993

 

"The Binding of Bovine Osteocalcin to Type I Collagen"

Richard V. Prigodich and Mark Vesely*

Gordon Research Conference on Calcium Phosphates - 1992

 

"Reaction of ssDNA with Hydroxyl Radical"

Richard V. Prigodich and Craig T. Martin

20th Meeting of the Federation of European Biochemical Societies - 1990

 

 

 

"Solid State NMR Studies of Cadmium Analogs of Hydroxyapatite"

Richard V. Prigodich

20th Meeting of the Federation of European Biochemical Societies - 1990

 

"Site-specific mutagenesis of T4 gene 32 - The role of aromatic-amino-acids in protein-nucleic acid interactions "

Yousif Shamoo, William Roberts, Richard Prigodich, Kenneth Williams, John Chase, Joseph Coleman and William Konigsberg

UCLA Symposium on Molecular and Cellular Biology -

Protein Structure and Design - April 1987

 

"Solution Structure of Osteocalcin: 1H, 31P and 113 Cd NMR Studies"

Richard V. Prigodich, Thomas O'Connor and Joseph Coleman

Gordon Research Conference on Proteins – 1985

 

"Solution Structure of Osteocalcin: 1H, 31P and 113Cd NMR Studies"

Richard V. Prigodich, Thomas O'Connor and Joseph Coleman

Federation of American Societies for Experimental Biology - 1984

 

"Aromatic Residues in the DNA Binding Grooves of Gene 5 and Gene 32 Proteins, 500 MHz 1H NMR"

Richard V. Prigodich and Joseph Coleman

Gordon Research Conference on Proteins - 1983