Research Interests

The overall goal of our research is the development of supercritical fluid extraction (SFE) technology as an efficient, cost-effective, and environmentally "friendly" alternative to traditional solvent-based sample preparation methods in clinical and/or forensic toxicological applications. Current projects include the development of 1) a rapid screening method for isolation and detection of drugs of the amphetamine class from human hair using on-line derivatization/SFE and GCMS, and 2) a method based on SFE/LC-MS for the isolation, identification, and quantification of anabolic steroids from human hair. Previous work involved the development of SFE/GC-MS and SFE/immunoassay methods for the analysis of cocaine in hair. Underlying objectives of our research include the investigation of the interactions which occur among analytes, biological matrixes, and supercritical fluids (SFs) and the mechanisms and kinetics that control these interactions; elucidation of the role of fluid modifiers and additives in improving analyte extractability; and the design of alternative coupled SFE-detection formats to produce rapid, simple screening methods for use in forensic or clinical laboratories.



Dr. Morrison poses with Jon Ashby while he presents the results of his research at the 238th National Meeting of the American Chemical Society in Washington, D.C. in August 2009. (for a larger version of this picture, please click on the image)
The Morrison lab poses for a photo after seminar, before getting back to the lab:
From left to right are: Kathryn McColl, Dr. Janet Morrison, Billy Burns, and Katie Harte. (for a larger version of this picture, please click on the image)
Kathryn McColl, gives a very nice presentation of her work at The Connecticut Valley Section of the American Chemical Institute (CVS-ACS) in the Spring of 2007.
Joe Cavar ('06) proudly displays the culmnination of his work for Dr. Morrison at the Northeast Regional American Chemical Society Meeting in the summer of 2005. (for a larger version of this picture, please click on the image)
Dr. Morrison is shown here with Craig Yennie.(for a larger version of this picture, please click on the image)
Tom Michalewski proudly displays the culmination of the research he accomplished while working for Dr. Morrison at Trinity College (for a larger version of this picture, please click on the image).
Dr. Morrison and Alison Rada pose for the camera while discussing new approaches to Alison's SFE work involving on-line derivatization/SFE.
Have scissors, will test hair!
Patrick King (left) and Terry Black (right) take a quick break from their research to pose for the camera with Dr. Janet Morrison