The Genomics Research Program at Trinity is a program designed for academically motivated students interested in the life sciences. Developed in affiliation with the Howard Hughes Medical Institute’s SEA-PHAGES initiative, it is a selective program for exceptional first year students that provides a biological research experience during the first two semesters of college, and a research seminar during the sophomore year. The GRP offers program-specific courses in which each student identifies and characterizes a non-pathogenic virus collected from the environment. From the viruses described, one is selected for complete genome sequencing. Students then explore genomic analysis by analyzing the genome structure - identifying new genes and adding them to the public gene databases. A student representative will present the class research at the end of the first year in a research symposium hosted by the Howard Hughes Medical Institute at their research campus in Virginia. The program is a unique opportunity to participate directly in the exciting area of genomics, and to experience biological discovery first-hand. The program is compatible with all majors at the College.
The Genomics Research Program begins in the fall semester of the first year with the FYSM 170 Phage Hunt course, in which students characterize viruses they collect from the environment (phage are viruses that attack bacteria). In the spring semester, students take Biol 175 Genome Analysis, in which students learn how to analyze the phage genome. The two first-year GRP-dedicated courses emphasize hands-on learning of current methods in genomics, DNA techniques, and electron microscopy. In the first year of the program students also take Biol.182 Evolution of Life in the fall, and Biol. 183 Cellular Basis of Life in the spring. These two introductory biology courses complement the research courses and provide the ecological, evolutionary, genetic and cellular contexts.
In the sophomore year, GRP students participate in a research seminar designed to introduce them to continuing research opportunities at Trinity and beyond and give them experience in reading and understanding primary research articles in all areas of biology. Collectively, the first and second year courses give students outstanding research training in very active areas of biological research.
The Genomics Research Program can accommodate only a limited number of students. Applicants for admission to Trinity who are interested in the program should write to Prof. Kathleen Archer for further details. In March of each year, those applicants to the College judged to be best qualified will be invited to become candidates for enrollment in the program.
II. Program Courses.
Fall, First Year: FYSM 170 Phage Hunt
Biol. 182 Evolution of Life
Spring, First Year: Biol. 175 Genome Analysis
Biol. 183 Cellular Basis of Life
Second Year: Biol. 250, Genomics Research Program seminar